P0 - P8 Rat Pineal Gland

Postnatal Rat Pineal Gland Tissue

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Fresh postnatal pineal gland brain tissue and media are provided to initiate a culture of primary rat neurons.

-          Melatonin production (derived from Tryptophan)

-          Serotonin production (derived from Tryptamine)

-          Circadian and Seasonal sleep cycles

-          Photoreceptor

• Thermoregulation
• Circadian Rhythm

-          Develops from roof of Diencephalon

-          Rich source of adrenergic neurons and pinealocytes

• Neurons sensitive to adrenal hormone epinephrine

-          Precocious puberty and delayed puberty have been associated with Pineal Gland tumors and cysts in humans; however the pathogenesis to these conditions is unclear.

-          17^th Century philosopher Rene Descartes believed the pineal gland to be the “seat of the soul” and responsible for cognition; however evidence is lacking to support this hypothesis.

Please click here for our Postnatal Primary Neuron Plating Protocol

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