E18 Mouse Pineal Gland

Fresh E18 tissue from C57 mouse and media are provided to initiate a culture of Pineal Gland.

Please Note: All E18 tissue is shipped for overnight delivery (required). All orders must be received 1 day prior to shipping date. Other mouse ages upon request.

-          Melatonin production (derived from Tryptophan)

-          Serotonin production (derived from Tryptamine)

-          Circadian and Seasonal sleep cycles

-          Photoreceptor

• Thermoregulation
• Circadian Rhythm

-          Develops from roof of Diencephalon

-          Rich source of adrenergic neurons and pinealocytes

• Neurons sensitive to adrenal hormone epinephrine

-          Precocious puberty and delayed puberty have been associated with Pineal Gland tumors and cysts in humans; however the pathogenesis to these conditions is unclear.

-          17^th Century philosopher Rene Descartes believed the pineal gland to be the “seat of the soul” and responsible for cognition; however evidence is lacking to support this hypothesis.

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